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Antigenic Specificity | Pancreas/duodenum Homeobox Protein 1 (PDX1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µl, |
Concentration | 1 mg/ml |
Applications | ELISA, WB, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2.The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression.Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
Immunogen | Purified recombinant fragment of human PDX1 expressed in E. coli. |
Other Names | GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1, PDHX, PDX1, Pyruvate dehydrogenase protein X component, mitochondrial, Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein, Lipoyl-containing pyruvate dehydrogenase complex component X, proX, Pancreas/duodenum homeobox protein 1, Glucose-sensitive factor, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, Somatostatin-transactivating factor 1, GSF, GSF, GSF , GSF , IPF1, IPF1, IPF1 , IPF1 , IUF1, IUF1, IUF1 , IUF1 , IDX-1, IDX-1, IDX-1 , IDX-1 , MODY4, MODY4, MODY4 , MODY4 , PDX-1, PDX-1, PDX-1 , PDX-1 , STF-1, STF-1, STF-1 , STF-1 , PDHX, PDHX, PDHX , PDHX , PDX1, PDX1, PDX1 , PDX1 , Pyruvate dehydrogenase protein X component, Pyruvate dehydrogenase protein X component, Pyruvate dehydrogenase protein X component , Pyruvate dehydrogenase protein X component , mitochondrial, mitochondrial, mitochondrial , mitochondrial , Dihydrolipoamide dehydrogenase-bi |
Gene, Accession # | PDX1, Gene ID: 3651, UniProt: P52945 |
Catalog # | abx015963 |
Price | please inquire |
Order / More Info | Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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