VAV1 (pY174) Antibody from ABBEXA LTD

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Antigenic SpecificityVAV1 (pY174)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size50 µl, 100 µl, 200 µl,
Concentration> 1 mg/ml
ApplicationsWB
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DescriptionVAV1 (pY174) antibody is a Rabbit polyclonal antibody against VAV1 (pY174). This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ImmunogenSynthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y174 of human VAV1.
Other NamesVAV1, p95vav, VAV, Vav 1 oncogene, Proto-oncogene vav, VAV1, VAV1, VAV1 , VAV1 , p95vav, p95vav, p95vav , p95vav , VAV, VAV, VAV , VAV , Vav 1 oncogene, Vav 1 oncogene, Vav 1 oncogene , Vav 1 oncogene , Proto-oncogene vav, Proto-oncogene vav, Proto-oncogene vav , Proto-oncogene vav
Gene, Accession #VAV1, Gene ID: 7409, UniProt: P15498
Catalog #abx000232
Priceplease inquire
Order / More InfoVAV1 (pY174) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950

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