Edit |   |
---|---|
Antigenic Specificity | Tyrosine-Protein Kinase ZAP-70 (ZAP70) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. |
Immunogen | KLH-conjugated synthetic peptide between 103-130 amino acids from the N-terminal region of human ZAP70. |
Other Names | ZAP70, zeta-chain (TCR) associated protein kinase 70kDa, FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70, 70 kDa zeta-associated protein, syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, zeta-chain associated protein kinase, 70kD, ZA70, kinase ZAP70, ZAP70, ZAP70, ZAP70 , ZAP70 , zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain (TCR) associated protein kinase 70kDa , zeta-chain (TCR) associated protein kinase 70kDa , FLJ17670, FLJ17670, FLJ17670 , FLJ17670 , FLJ17679, FLJ17679, FLJ17679 , FLJ17679 , SRK, SRK, SRK , SRK , STD, STD, STD , STD , TZK, TZK, TZK , TZK , ZAP-70, ZAP-70, ZAP-70 , ZAP-70 , 70 kDa zeta-associated protein, 70 kDa zeta-associated protein, 70 kDa zeta-associated protein , 70 kDa zeta-associated protein , syk-related tyrosine kinase, syk-related tyrosine kinase, syk-related tyrosine kinase , syk-related tyrosine kinase , tyrosine-protein kinase ZAP-70, tyrosine-protein kinase ZAP-70, tyro |
Gene, Accession # | ZAP70, UniProt: P43403 |
Catalog # | abx027829 |
Price | please inquire |
Order / More Info | Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950