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Antigenic Specificity | RE1 Silencing Transcription Factor (REST) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. |
Immunogen | KLH-conjugated synthetic peptide between 542-570 amino acids from the Central region of human REST. |
Other Names | REST, NRSF, XBR, RE1-silencing transcription factor, Neural-restrictive silencer factor, X2 box repressor, REST, REST, REST , REST , NRSF, NRSF, NRSF , NRSF , XBR, XBR, XBR , XBR , RE1-silencing transcription factor, RE1-silencing transcription factor, RE1-silencing transcription factor , RE1-silencing transcription factor , Neural-restrictive silencer factor, Neural-restrictive silencer factor, Neural-restrictive silencer factor , Neural-restrictive silencer factor , X2 box repressor, X2 box repressor, X2 box repressor , X2 box repressor |
Gene, Accession # | UniProt: Q13127 |
Catalog # | abx029206 |
Price | please inquire |
Order / More Info | RE1 Silencing Transcription Factor (REST) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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