DDR2 (TYRO10) Antibody from ABBEXA LTD
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| Antigenic Specificity | DDR2 (TYRO10) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs. |
| Immunogen | KLH-conjugated synthetic peptide between 290-320 amino acids from human DDR2 (TYRO10). |
| Other Names | DDR2, NTRKR3, TKT, TYRO10, Discoidin domain-containing receptor 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD167b, DDR2, DDR2, DDR2 , DDR2 , NTRKR3, NTRKR3, NTRKR3 , NTRKR3 , TKT, TKT, TKT , TKT , TYRO10, TYRO10, TYRO10 , TYRO10 , Discoidin domain-containing receptor 2, Discoidin domain-containing receptor 2, Discoidin domain-containing receptor 2 , Discoidin domain-containing receptor 2 , CD167 antigen-like family member B, CD167 antigen-like family member B, CD167 antigen-like family member B , CD167 antigen-like family member B , Discoidin domain-containing receptor tyrosine kinase 2, Discoidin domain-containing receptor tyrosine kinase 2, Discoidin domain-containing receptor tyrosine kinase 2 , Discoidin domain-containing receptor tyrosine kinase 2 , Neurotrophic tyrosine kinase, Neurotrophic tyrosine kin |
| Gene, Accession # | NCBI: NP_001014796.1, NP_006173.2, UniProt: Q16832 |
| Catalog # | abx033620 |
| Price | please inquire |
| Order / More Info | DDR2 (TYRO10) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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