Ran GTPase-Activating Protein 1 (RANGAP1) Antibody from ABBEXA LTD

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Antigenic SpecificityRan GTPase-Activating Protein 1 (RANGAP1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionRanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
ImmunogenKLH-conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1.
Other NamesKIAA1835, SD, Ran GTPase-activating protein 1, RanGAP1, Ran GTPase activating protein 1, Fug1, MGC20266, OTTHUMP00000198756, OTTHUMP00000198757, segregation distorter homolog, segregation distortion, RANGAP, KIAA1835, KIAA1835, KIAA1835 , KIAA1835 , SD, SD, SD , SD , Ran GTPase-activating protein 1, Ran GTPase-activating protein 1, Ran GTPase-activating protein 1 , Ran GTPase-activating protein 1 , RanGAP1, RanGAP1, RanGAP1 , RanGAP1 , Ran GTPase activating protein 1, Ran GTPase activating protein 1, Ran GTPase activating protein 1 , Ran GTPase activating protein 1 , Fug1, Fug1, Fug1 , Fug1 , MGC20266, MGC20266, MGC20266 , MGC20266 , OTTHUMP00000198756, OTTHUMP00000198756, OTTHUMP00000198756 , OTTHUMP00000198756 , OTTHUMP00000198757, OTTHUMP00000198757, OTTHUMP00000198757 , OTTHUMP00000198757 , segregation distorter homolog, segregation distorter homolog, segregation distorter homolog , segregation distorter homolog , segregation distortion, segregation distortion, segregati
Gene, Accession #UniProt: P46060
Catalog #abx027599
Priceplease inquire
Order / More InfoRan GTPase-Activating Protein 1 (RANGAP1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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