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Antigenic Specificity | Ran GTPase-Activating Protein 1 (RANGAP1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. |
Immunogen | KLH-conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1. |
Other Names | KIAA1835, SD, Ran GTPase-activating protein 1, RanGAP1, Ran GTPase activating protein 1, Fug1, MGC20266, OTTHUMP00000198756, OTTHUMP00000198757, segregation distorter homolog, segregation distortion, RANGAP, KIAA1835, KIAA1835, KIAA1835 , KIAA1835 , SD, SD, SD , SD , Ran GTPase-activating protein 1, Ran GTPase-activating protein 1, Ran GTPase-activating protein 1 , Ran GTPase-activating protein 1 , RanGAP1, RanGAP1, RanGAP1 , RanGAP1 , Ran GTPase activating protein 1, Ran GTPase activating protein 1, Ran GTPase activating protein 1 , Ran GTPase activating protein 1 , Fug1, Fug1, Fug1 , Fug1 , MGC20266, MGC20266, MGC20266 , MGC20266 , OTTHUMP00000198756, OTTHUMP00000198756, OTTHUMP00000198756 , OTTHUMP00000198756 , OTTHUMP00000198757, OTTHUMP00000198757, OTTHUMP00000198757 , OTTHUMP00000198757 , segregation distorter homolog, segregation distorter homolog, segregation distorter homolog , segregation distorter homolog , segregation distortion, segregation distortion, segregati |
Gene, Accession # | UniProt: P46060 |
Catalog # | abx027599 |
Price | please inquire |
Order / More Info | Ran GTPase-Activating Protein 1 (RANGAP1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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