Glutamate Decarboxylase 1 (GAD1) Antibody from ABBEXA LTD

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Antigenic SpecificityGlutamate Decarboxylase 1 (GAD1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size100 µg,
Concentration2 mg/ml
ApplicationsELISA, WB
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DescriptionGlutamate Decarboxylase 1 (GAD1) antibody is a Rabbit polyclonal antibody for the detection of GAD1.

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Immunogenglutamate decarboxylase 1
Other NamesGAD1, Glutamate Decarboxylase 1, Glutamate Decarboxylase 1 (Brain, 67kDa), Glutamate Decarboxylase 67 KDa Isoform, 67 KDa Glutamic Acid Decarboxylase, GAD-67, GAD, Glutamate Decarboxylase 1 (Brain, 67kD), EC 4.1.1.15, CPSQ1, GAD67, SCP, GAD1, GAD1, GAD1 , GAD1 , Glutamate Decarboxylase 1, Glutamate Decarboxylase 1, Glutamate Decarboxylase 1 , Glutamate Decarboxylase 1 , Glutamate Decarboxylase 1 (Brain, 67kDa), Glutamate Decarboxylase 1 (Brain, 67kDa), Glutamate Decarboxylase 1 (Brain, 67kDa) , Glutamate Decarboxylase 1 (Brain, 67kDa) , Glutamate Decarboxylase 67 KDa Isoform, Glutamate Decarboxylase 67 KDa Isoform, Glutamate Decarboxylase 67 KDa Isoform , Glutamate Decarboxylase 67 KDa Isoform , 67 KDa Glutamic Acid Decarboxylase, 67 KDa Glutamic Acid Decarboxylase, 67 KDa Glutamic Acid Decarboxylase , 67 KDa Glutamic Acid Decarboxylase , GAD-67, GAD-67, GAD-67 , GAD-67 , GAD, GAD, GAD , GAD , Glutamate Decarboxylase 1 (Brain, 67kD), Glutamate Decarboxylase 1 (Brain, 67kD), Glu
Gene, Accession #GAD1, Gene ID: 2571, NCBI: NP_000808.2, UniProt: Q99259
Catalog #abx215526
Priceplease inquire
Order / More InfoGlutamate Decarboxylase 1 (GAD1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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