Calsyntenin 1 (CLSTN1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Calsyntenin 1 (CLSTN1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity). |
| Immunogen | KLH-conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human CLSTN1. |
| Other Names | CLSTN1, Alcadein-alpha, Alcadein alpha 1, Alcalpha2, Alcalpha1, CS1, CSTN1, CDHR12, ALC-ALPHA, XB31alpha, Calsyntenin 1, Calsyntenin-1, KIAA0911, Alzheimer-related cadherin-like protein, Non-classical cadherin XB31alpha, Soluble Alc-alpha, CTF1-alpha, C-terminal fragment 1-alpha, PIK3CD, CLSTN1, CLSTN1, CLSTN1 , CLSTN1 , Alcadein-alpha, Alcadein-alpha, Alcadein-alpha , Alcadein-alpha , Alcadein alpha 1, Alcadein alpha 1, Alcadein alpha 1 , Alcadein alpha 1 , Alcalpha2, Alcalpha2, Alcalpha2 , Alcalpha2 , Alcalpha1, Alcalpha1, Alcalpha1 , Alcalpha1 , CS1, CS1, CS1 , CS1 , CSTN1, CSTN1, CSTN1 , CSTN1 , CDHR12, CDHR12, CDHR12 , CDHR12 , ALC-ALPHA, ALC-ALPHA, ALC-ALPHA , ALC-ALPHA , XB31alpha, XB31alpha, XB31alpha , XB31alpha , Calsyntenin 1, Calsyntenin 1, Calsyntenin 1 , Calsyntenin 1 , Calsyntenin-1, Calsyntenin-1, Calsyntenin-1 , Calsyntenin-1 , KIAA0911, KIAA0911, KIAA0911 , KIAA0911 , Alzheimer-related cadherin-like protein, Alzheimer-related cadherin-like protein, Alzhe |
| Gene, Accession # | CLSTN1, UniProt: O94985 |
| Catalog # | abx030664 |
| Price | please inquire |
| Order / More Info | Calsyntenin 1 (CLSTN1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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