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Antigenic Specificity | EGFR (pY1125) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. A prototype member of the type 1 receptor tyrosine kinases, EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. Increased production or activation of EGFR has been associated with poor prognosis in a variety of tumors. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1125 of human EGFR. |
Other Names | EGFR, epidermal growth factor receptor, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, Receptor protein-tyrosine kinase ErbB-1, erbb 1, Receptor tyrosine protein kinase ErbB 1, PIG61, HGNC:3236, ERBB, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, epidermal growth fac, HER1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, Epidermal growth factor receptor precursor, kinase EGFR, EGFR, EGFR, EGFR , EGFR , epidermal growth factor receptor, epidermal growth factor receptor, epidermal growth factor receptor , epidermal growth factor receptor , erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian , erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian , Receptor protein-tyrosine kinase ErbB-1, Receptor protein-tyrosine kinase ErbB-1, Receptor protein-tyrosine kinase ErbB-1 , |
Gene, Accession # | UniProt: P00533 |
Catalog # | abx031963 |
Price | please inquire |
Order / More Info | EGFR (pY1125) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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