PTPN6 (pY536) Antibody from ABBEXA LTD

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Antigenic SpecificityPTPN6 (pY536)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size50 µl, 100 µl, 200 µl,
Concentration> 0.5 mg/ml
ApplicationsWB, IHC, IF/ICC
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DescriptionPTPN6 (pY536) antibody is a Rabbit polyclonal antibody against PTPN6 (pY536). The protein encoded by this gene is a member of the protein tyrosine phosphatase (pYP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein pTosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.
ImmunogenSynthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y536 of human PTPN6.
Other NamesHematopoietic Cell Protein-Tyrosine Phosphatase, Protein-Tyrosine Phosphatase 1C, Ptp-1C, Protein-Tyrosine Phosphatase Shp-1, Sh-Ptp1, Ptpn6, Hcp, Ptp1C, HCPH, HPTP1C, SHP-1, SHP-1L, SHP1, Tyrosine-protein phosphatase non-receptor type 6, Hematopoietic Cell Protein-Tyrosine Phosphatase, Hematopoietic Cell Protein-Tyrosine Phosphatase, Hematopoietic Cell Protein-Tyrosine Phosphatase , Hematopoietic Cell Protein-Tyrosine Phosphatase , Protein-Tyrosine Phosphatase 1C, Protein-Tyrosine Phosphatase 1C, Protein-Tyrosine Phosphatase 1C , Protein-Tyrosine Phosphatase 1C , Ptp-1C, Ptp-1C, Ptp-1C , Ptp-1C , Protein-Tyrosine Phosphatase Shp-1, Protein-Tyrosine Phosphatase Shp-1, Protein-Tyrosine Phosphatase Shp-1 , Protein-Tyrosine Phosphatase Shp-1 , Sh-Ptp1, Sh-Ptp1, Sh-Ptp1 , Sh-Ptp1 , Ptpn6, Ptpn6, Ptpn6 , Ptpn6 , Hcp, Hcp, Hcp , Hcp , Ptp1C, Ptp1C, Ptp1C , Ptp1C , HCPH, HCPH, HCPH , HCPH , HPTP1C, HPTP1C, HPTP1C , HPTP1C , SHP-1, SHP-1, SHP-1 , SHP-1 , SHP-1L, SHP-1L, SHP-1L , SH
Gene, Accession #PTPN6, Gene ID: 5777, UniProt: P29350
Catalog #abx000487
Priceplease inquire
Order / More InfoPTPN6 (pY536) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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