Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Interferon Induced With Helicase C Domain 1 (IFIH1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | 0.75 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IFIH1 antibody is a Rabbit polyclonal antibody against IFIH1. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. |
| Immunogen | Recombinant protein of human IFIH1. |
| Other Names | Clinically amyopathic dermatomyositis autoantigen 140 kDa, CADM-140 autoantigen, Helicase with 2 CARD domains, Helicard, Interferon-induced with helicase C domain protein 1, Melanoma differentiation-associated protein 5, MDA-5, Murabutide down-regulated protein, RIG-I-like receptor 2, RLR-2, RNA helicase-DEAD box protein 116, IFIH1, MDA5, RH116, Hlcd, IDDM19, MGC133047, Interferon Induced Helicase C Domain Containing Protein 1, Interferon-induced helicase C domain-containing protein 1, M, Clinically amyopathic dermatomyositis autoantigen 140 kDa, Clinically amyopathic dermatomyositis autoantigen 140 kDa, Clinically amyopathic dermatomyositis autoantigen 140 kDa , Clinically amyopathic dermatomyositis autoantigen 140 kDa , CADM-140 autoantigen, CADM-140 autoantigen, CADM-140 autoantigen , CADM-140 autoantigen , Helicase with 2 CARD domains, Helicase with 2 CARD domains, Helicase with 2 CARD domains , Helicase with 2 CARD domains , Helicard, Helicard, Helicard , Helicard , Interferon |
| Gene, Accession # | IFIH1, Gene ID: 64135, UniProt: Q9BYX4 |
| Catalog # | abx001815 |
| Price | please inquire |
| Order / More Info | Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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