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Antigenic Specificity | DNA Polymerase Eta (POLH) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | POLH antibody is a Rabbit polyclonal antibody against POLH. This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein of human POLH. |
Other Names | DNA polymerase eta, RAD30 homolog A, Xeroderma pigmentosum variant type protein, POLH, RAD30, RAD30A, XPV, FLJ16395, FLJ21978, XP-V, DNA polymerase eta, DNA polymerase eta, DNA polymerase eta , DNA polymerase eta , RAD30 homolog A, RAD30 homolog A, RAD30 homolog A , RAD30 homolog A , Xeroderma pigmentosum variant type protein, Xeroderma pigmentosum variant type protein, Xeroderma pigmentosum variant type protein , Xeroderma pigmentosum variant type protein , POLH, POLH, POLH , POLH , RAD30, RAD30, RAD30 , RAD30 , RAD30A, RAD30A, RAD30A , RAD30A , XPV, XPV, XPV , XPV , FLJ16395, FLJ16395, FLJ16395 , FLJ16395 , FLJ21978, FLJ21978, FLJ21978 , FLJ21978 , XP-V, XP-V, XP-V , XP-V |
Gene, Accession # | POLH, Gene ID: 5429, UniProt: Q9Y253 |
Catalog # | abx001515 |
Price | please inquire |
Order / More Info | DNA Polymerase Eta (POLH) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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