PDPK1 (pS396) Antibody from ABBEXA LTD
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| Antigenic Specificity | PDPK1 (pS396) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3, 4, 5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis. Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S396 of human PDPK1. |
| Other Names | 3-phosphoinositide-dependent protein kinase 1, hPDK1, PDPK1, PDK1, PDPK2, PRO0461, 3-phosphoinositide-dependent protein kinase 1, 3-phosphoinositide-dependent protein kinase 1, 3-phosphoinositide-dependent protein kinase 1 , 3-phosphoinositide-dependent protein kinase 1 , hPDK1, hPDK1, hPDK1 , hPDK1 , PDPK1, PDPK1, PDPK1 , PDPK1 , PDK1, PDK1, PDK1 , PDK1 , PDPK2, PDPK2, PDPK2 , PDPK2 , PRO0461, PRO0461, PRO0461 , PRO0461 |
| Gene, Accession # | UniProt: O15530 |
| Catalog # | abx031991 |
| Price | please inquire |
| Order / More Info | PDPK1 (pS396) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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