Protein Phosphatase, Mg2+/Mn2+ Dependent 1A (PPM1A) Antibody from ABBEXA LTD
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| Antigenic Specificity | Protein Phosphatase, Mg2+/Mn2+ Dependent 1A (PPM1A) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Immunogen | KLH-conjugated synthetic peptide between 355-382 amino acids from human PPM1A. |
| Other Names | PP2CA, PP2Calpha, PP2C-ALPHA, PPM1A, PPPM1A, Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, Protein phosphatase IA, protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform, FLJ42306, MGC9201, PP2CA, PP2CA, PP2CA , PP2CA , PP2Calpha, PP2Calpha, PP2Calpha , PP2Calpha , PP2C-ALPHA, PP2C-ALPHA, PP2C-ALPHA , PP2C-ALPHA , PPM1A, PPM1A, PPM1A , PPM1A , PPPM1A, PPPM1A, PPPM1A , PPPM1A , Protein phosphatase 1A, Protein phosphatase 1A, Protein phosphatase 1A , Protein phosphatase 1A , Protein phosphatase 2C isoform alpha, Protein phosphatase 2C isoform alpha, Protein phosphatase 2C isoform alpha , Protein phosphatase 2C isoform alpha , Protein phosphatase IA, Protein phosphatase IA, Protein phosphatase IA , Protein phosphatase IA , protein phosphatase 1A (formerly 2C), protein phosphatase 1A (formerly 2C), protein phosphatase 1A (formerly 2C) , protein phosphatase 1A (formerly 2C) , magnesium-dependent, magnesium-dependent, magnesium-dependent , magnesiu |
| Gene, Accession # | PPM1A, UniProt: P35813 |
| Catalog # | abx027960 |
| Price | please inquire |
| Order / More Info | Protein Phosphatase, Mg2+/Mn2+ Dependent 1A (PPM1A) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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