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Antigenic Specificity | 26S Proteasome Non-ATPase Regulatory Subunit 12 (PSMD12) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 26S Proteasome Non-ATPase Regulatory Subunit 12 (PSMD12) antibody is a Rabbit polyclonal antibody against 26S Proteasome Non-ATPase Regulatory Subunit 12 (PSMD12). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Human PSMD12. |
Other Names | 26S proteasome non-ATPase regulatory 12, 26S proteasome regulatory p55, proteasome (prosome, macropain) 26S, non-ATPase, 12, proteasome 26S non-ATPase 12, proteasome 26S non-ATPase 12 isoform 1 variant, PSD12, 26S proteasome non-ATPase regulatory subunit 12, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit p55, PSMD12, p55, Rpn5, macropain) 26S subunit, MGC75406, 26S proteasome non-ATPase regulatory 12, 26S proteasome non-ATPase regulatory 12, 26S proteasome non-ATPase regulatory 12 , 26S proteasome non-ATPase regulatory 12 , 26S proteasome regulatory p55, 26S proteasome regulatory p55, 26S proteasome regulatory p55 , 26S proteasome regulatory p55 , proteasome (prosome, proteasome (prosome, proteasome (prosome , proteasome (prosome , macropain) 26S, macropain) 26S, macropain) 26S , macropain) 26S , non-ATPase, non-ATPase, non-ATPase , non-ATPase , 12, 12, 12 , 12 , proteasome 26S non-ATPase 12, proteasome 26S non-ATPase 12, proteasome 26S non-ATPase 12 , |
Gene, Accession # | PSMD12, Gene ID: 5718, NCBI: NP_001303270.1, NM_001316341.1, NP_002807.1, NM_002816.4, UniProt: O00232 |
Catalog # | abx114746 |
Price | please inquire |
Order / More Info | 26S Proteasome Non-ATPase Regulatory Subunit 12 (PSMD12) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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