Edit |   |
---|---|
Antigenic Specificity | Histone Deacetylase 5 Phospho-Ser498 (HDAC5 pS498) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl, |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HDAC5 (pS498) antibody is a Rabbit polyclonal antibody against HDAC5 (pS498). Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S498 of human HDAC5. |
Other Names | Antigen NY-CO-9, FLJ90614, HD5, HDAC5, Histone deacetylase 5, KIAA0600, NY-CO-9, Histone deacetylase mHDA1, DKFZp779K1053, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9, HDAC9B, HDAC9FL, HDRP, histone deacetylase 4/5-related protein, histone deacetylase 7, Histone deacetylase 7B, Histone deacetylase 9, Histone deacetylase-related protein, KIAA0744, MEF-2 interacting transcription repressor (MITR) protein, MEF2-interacting transcription repressor MITR, MITR, Antigen NY-CO-9, Antigen NY-CO-9, Antigen NY-CO-9 , Antigen NY-CO-9 , FLJ90614, FLJ90614, FLJ90614 , FLJ90614 , HD5, HD5, HD5 , HD5 , HDAC5, HDAC5, HDAC5 , HDAC5 , Histone deacetylase 5, Histone deacetylase 5, Histone deacetylase 5 , Histone deacetylase 5 , KIAA0600, KIAA0600, KIAA0600 , KIAA0600 , NY-CO-9, NY-CO-9, NY-CO-9 , NY-CO-9 , Histone deacetylase mHDA1, Histone deacetylase mHDA1, Histone deacetylase mHDA1 , Histone deacetylase mHDA1 , DKFZp779K1053, DKFZp779K1053, DKFZp779K1053 , DKFZp779K1053 , HD7, HD7, HD7 , HD7 , |
Gene, Accession # | HDAC5, Gene ID: 10014, UniProt: Q9UQL6 |
Catalog # | abx000254 |
Price | please inquire |
Order / More Info | Histone Deacetylase 5 Phospho-Ser498 (HDAC5 pS498) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950