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Antigenic Specificity | Protease Activated Receptor 4 (PAR4) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis.It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults.Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration.The tumor suppressor WT1 represses and activates transcription.The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor.Par4 is a WT1 interacting protein that also functions as a transcriptional repressor. |
Immunogen | Purified recombinant fragment of PAR4 (aa1-330) expressed in E. coli. |
Other Names | coagulation factor II (thrombin) receptor-like 3, coagulation factor II receptor-like 3, F2RL3, PAR-4, protease-activated receptor-4, proteinase-activated receptor 4, thrombin receptor-like 3, PAR4, PAWR, coagulation factor II (thrombin) receptor-like 3, coagulation factor II (thrombin) receptor-like 3, coagulation factor II (thrombin) receptor-like 3 , coagulation factor II (thrombin) receptor-like 3 , coagulation factor II receptor-like 3, coagulation factor II receptor-like 3, coagulation factor II receptor-like 3 , coagulation factor II receptor-like 3 , F2RL3, F2RL3, F2RL3 , F2RL3 , PAR-4, PAR-4, PAR-4 , PAR-4 , protease-activated receptor-4, protease-activated receptor-4, protease-activated receptor-4 , protease-activated receptor-4 , proteinase-activated receptor 4, proteinase-activated receptor 4, proteinase-activated receptor 4 , proteinase-activated receptor 4 , thrombin receptor-like 3, thrombin receptor-like 3, thrombin receptor-like 3 , thrombin receptor-like 3 , PA |
Gene, Accession # | PAWR, Gene ID: 5074, UniProt: Q96IZ0 |
Catalog # | abx016047 |
Price | please inquire |
Order / More Info | Protease Activated Receptor 4 (PAR4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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