TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) Antibody from ABBEXA LTD
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| Antigenic Specificity | TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FAS Antibody is a Rabbit Polyclonal antibody against FAS. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. |
| Immunogen | Recombinant protein of human FAS. |
| Other Names | FAS, Fas Cell Surface Death Receptor, Tumor Necrosis Factor Receptor Superfamily, Member 6, Tumor Necrosis Factor Receptor Superfamily Member 6, Fas (TNF Receptor Superfamily, Member 6), Apoptosis-Mediating Surface Antigen FAS, TNF Receptor Superfamily Member 6, FASLG Receptor, CD95 Antigen, TNFRSF6, APT1, FAS1, Mutant Tumor Necrosis Receptor Superfamily Member 6, Apoptosis Signaling Receptor FAS, APO-1 Cell Surface Antigen, Apoptosis Antigen 1, Apo-1 Antigen, Fas AMA, ALPS1A, APO-1, FASTM, CD95, Factor Related Apoptosis,, FAS, FAS, FAS, FAS, Fas Cell Surface Death Receptor, Fas Cell Surface Death Receptor, Fas Cell Surface Death Receptor, Fas Cell Surface Death Receptor, Tumor Necrosis Factor Receptor Superfamily, Member 6, Tumor Necrosis Factor Receptor Superfamily, Member 6, Tumor Necrosis Factor Receptor Superfamily, Member 6, Tumor Necrosis Factor Receptor Superfamily, Member 6, Tumor Necrosis Factor Receptor Superfamily Member 6, Tumor Necrosis Factor Receptor Superfamily Member 6, Tumor Necrosis Factor Receptor Superfamily Member 6, Tumor Necrosis Factor Receptor Superfamily Member 6, Fas (TNF Receptor Superfamily, Member 6), Fas (TNF Receptor Superfamily, Member 6), Fas (TNF Receptor Superfamily, Member 6), Fas (TNF Receptor Superfamily, Member 6), Apoptosis-Mediating Surface Antigen FAS, Apoptosis-Mediating Surface Antigen FAS, Apoptosis-Mediating Surface Antigen FAS, Apoptosis-Mediating Surface Antigen FAS, TNF Receptor Superfamily Member 6, TNF Receptor Superfamily Member 6, TNF Receptor Superfamily Member 6, TNF Receptor Superfamily Member 6, FASLG Receptor, FASLG Receptor, FASLG Receptor, FASLG Receptor, CD95 Antigen, CD95 Antigen, CD95 Antigen, CD95 Antigen, TNFRSF6, TNFRSF6, TNFRSF6, TNFRSF6, APT1, APT1, APT1, APT1, FAS1, FAS1, FAS1, FAS1, Mutant Tumor Necrosis Receptor Superfamily Member 6, Mutant Tumor Necrosis Receptor Superfamily Member 6, Mutant Tumor Necrosis Receptor Superfamily Member 6, Mutant Tumor Necrosis Receptor Superfamily Member 6, Apoptosis Signaling Receptor FAS, Apoptosis Signaling Receptor FAS, Apoptosis Signaling Receptor FAS, Apoptosis Signaling Receptor FAS, APO-1 Cell Surface Antigen, APO-1 Cell Surface Antigen, APO-1 Cell Surface Antigen, APO-1 Cell Surface Antigen, Apoptosis Antigen 1, Apoptosis Antigen 1, Apoptosis Antigen 1, Apoptosis Antigen 1, Apo-1 Antigen, Apo-1 Antigen, Apo-1 Antigen, Apo-1 Antigen, Fas AMA, Fas AMA, Fas AMA, Fas AMA, ALPS1A, ALPS1A, ALPS1A, ALPS1A, APO-1, APO-1, APO-1, APO-1, FASTM, FASTM, FASTM, FASTM, CD95, CD95, CD95, CD95, Factor Related Apoptosis, Factor Related Apoptosis, Factor Related Apoptosis, Factor Related Apoptosis,,,, |
| Gene, Accession # | FAS, Gene ID: 355, UniProt: P25445 |
| Catalog # | abx000618 |
| Price | please inquire |
| Order / More Info | TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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