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Antigenic Specificity | Poly(RC) Binding Protein 1 (PCBP1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC) binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. |
Immunogen | KLH-conjugated synthetic peptide between 188-217 amino acids from the Central region of human PCBP1. |
Other Names | PCBP1, Poly (rC) binding protein 1, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, Nucleic acid-binding protein SUB2.3, Poly(rC)-binding protein 1, hnRNP E1, PCBP1, PCBP1, PCBP1 , PCBP1 , Poly (rC) binding protein 1, Poly (rC) binding protein 1, Poly (rC) binding protein 1 , Poly (rC) binding protein 1 , Alpha-CP1, Alpha-CP1, Alpha-CP1 , Alpha-CP1 , Heterogeneous nuclear ribonucleoprotein E1, Heterogeneous nuclear ribonucleoprotein E1, Heterogeneous nuclear ribonucleoprotein E1 , Heterogeneous nuclear ribonucleoprotein E1 , Nucleic acid-binding protein SUB2.3, Nucleic acid-binding protein SUB2.3, Nucleic acid-binding protein SUB2.3 , Nucleic acid-binding protein SUB2.3 , Poly(rC)-binding protein 1, Poly(rC)-binding protein 1, Poly(rC)-binding protein 1 , Poly(rC)-binding protein 1 , hnRNP E1, hnRNP E1, hnRNP E1 , hnRNP E1 |
Gene, Accession # | UniProt: Q15365 |
Catalog # | abx030587 |
Price | please inquire |
Order / More Info | Poly(RC) Binding Protein 1 (PCBP1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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