PTPN11 (pY542) Antibody from ABBEXA LTD
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| Antigenic Specificity | PTPN11 (pY542) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µl, 100 µl, 200 µl, |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PTPN11 (pY542) antibody is a Rabbit polyclonal antibody against PTPN11 (pY542). The protein encoded by this gene is a member of the protein tyrosine phosphatase (pYP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as pTosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y542 of human PTPN11. |
| Other Names | BPTP3, CFC, MGC14433, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2, SH-PTP, PTPN11, SHPTP2, Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), SHP-2, Noonan syndrome 1, protein tyrosine phosphatase, non-receptor type 11, PTP-2C, BPTP3, BPTP3, BPTP3 , BPTP3 , CFC, CFC, CFC , CFC , MGC14433, MGC14433, MGC14433 , MGC14433 , NS1, NS1, NS1 , NS1 , PTP-1D, PTP-1D, PTP-1D , PTP-1D , PTP2C, PTP2C, PTP2C , PTP2C , SH-PTP2, SH-PTP2, SH-PTP2 , SH-PTP2 , SH-PTP3, SH-PTP3, SH-PTP3 , SH-PTP3 , SHP2, SHP2, SHP2 , SHP2 , SH-PTP, SH-PTP, SH-PTP , SH-PTP , PTPN11, PTPN11, PTPN11 , PTPN11 , SHPTP2, SHPTP2, SHPTP2 , SHPTP2 , Tyrosine-protein phosphatase non-receptor type 11, Tyrosine-protein phosphatase non-receptor type 11, Tyrosine-protein phosphatase non-receptor type 11 , Tyrosine-protein phosphatase non-receptor type 11 , Protein-tyrosine phosphatase 1D, |
| Gene, Accession # | PTPN11, Gene ID: 5781, UniProt: Q06124 |
| Catalog # | abx000318 |
| Price | please inquire |
| Order / More Info | PTPN11 (pY542) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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