Edit |   |
---|---|
Antigenic Specificity | FK506 Binding Protein 1A (FKBP1A) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FKBP1A antibody is a Rabbit polyclonal antibody against FKBP1A. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008]. |
Immunogen | Recombinant protein of human FKBP1A. |
Other Names | FKBP1, PKC12, PKCI2, FKBP12, PPIASE, FKBP-12, FKBP-1A, FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, 12 kDa FK506-binding protein, Calstabin-1, FK506-binding protein 1A, Immunophilin FKBP12, Rotamase, PPIase FKBP1A, 12 kDa FKBP, FKBP1, FKBP1, FKBP1 , FKBP1 , PKC12, PKC12, PKC12 , PKC12 , PKCI2, PKCI2, PKCI2 , PKCI2 , FKBP12, FKBP12, FKBP12 , FKBP12 , PPIASE, PPIASE, PPIASE , PPIASE , FKBP-12, FKBP-12, FKBP-12 , FKBP-12 , FKBP-1A, FKBP-1A, FKBP-1A , FKBP-1A , FKBP1A, FKBP1A, FKBP1A , FKBP1A , Peptidyl-prolyl cis-trans isomerase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A , Peptidyl-prolyl cis-trans isomerase FKBP1A , 12 kDa FK506-binding protein, 12 kDa FK506-binding protein, 12 kDa FK506-binding protein , 12 kDa FK506-binding protein , Calstabin-1, Calstabin-1, Calstabin-1 , Calstabin-1 , FK506-binding protein 1A, FK506-binding protein 1A, FK506-binding protein 1A , FK506-binding protein 1A , Immunophilin FKBP12, Imm |
Gene, Accession # | FKBP1A, Gene ID: 2280, UniProt: P62942 |
Catalog # | abx001462 |
Price | please inquire |
Order / More Info | FK506 Binding Protein 1A (FKBP1A) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950