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Antigenic Specificity | Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, monkey |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance.It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure.Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta.Low expression in small intestine, liver and colon. |
Immunogen | Purified recombinant fragment of human ABCG2 expressed in E. coli. |
Other Names | BMDP, MRX, ABC15, ABCP, BCRP1, ABCG2, ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group), BCRP, CD338, CDw338, EST157481, GOUT1, MXR, MXR1, UAQTL1, MXR-1, BMDP, BMDP, BMDP , BMDP , MRX, MRX, MRX , MRX , ABC15, ABC15, ABC15 , ABC15 , ABCP, ABCP, ABCP , ABCP , BCRP1, BCRP1, BCRP1 , BCRP1 , ABCG2, ABCG2, ABCG2 , ABCG2 , ATP-binding cassette, ATP-binding cassette, ATP-binding cassette , ATP-binding cassette , sub-family G (WHITE), sub-family G (WHITE), sub-family G (WHITE) , sub-family G (WHITE) , member 2 (Junior blood group), member 2 (Junior blood group), member 2 (Junior blood group) , member 2 (Junior blood group) , BCRP, BCRP, BCRP , BCRP , CD338, CD338, CD338 , CD338 , CDw338, CDw338, CDw338 , CDw338 , EST157481, EST157481, EST157481 , EST157481 , GOUT1, GOUT1, GOUT1 , GOUT1 , MXR, MXR, MXR , MXR , MXR1, MXR1, MXR1 , MXR1 , UAQTL1, UAQTL1, UAQTL1 , UAQTL1 , MXR-1, MXR-1, MXR-1 , MXR-1 |
Gene, Accession # | Gene ID: 9429 |
Catalog # | abx015756 |
Price | please inquire |
Order / More Info | Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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