Edit |   |
---|---|
Antigenic Specificity | B-Cell Lymphoma/leukemia 10 (BCL10) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. |
Immunogen | KLH-conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human BCL10. |
Other Names | B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, BCL10, CARD- containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CED- 3/ICH-1 prodomain homologous E10-like regulator, CIPER, CLAP, Cellular homolog of vCARMEN, Cellular-E10, Mammali, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, cCARMEN, c-E10, Mammalian CARD-containing adapter molecule E10, mE10, CARMEN, B-cell CLL/lymphoma 10, B-cell CLL/lymphoma 10, B-cell CLL/lymphoma 10 , B-cell CLL/lymphoma 10 , B-cell lymphoma/leukemia 10, B-cell lymphoma/leukemia 10, B-cell lymphoma/leukemia 10 , B-cell lymphoma/leukemia 10 , BCL10, BCL10, BCL10 , BCL10 , CARD- containing molecule enhancing NF-kappa-B, CARD- containing molecule enhancing NF-kappa-B, CARD- containing molecule enhancing NF-kappa-B , CARD- containing molecule enhancing NF-kappa-B , CARD-like apoptotic protein, CARD-like apoptotic protein, CARD-like apoptotic protein , CARD-like apoptoti |
Gene, Accession # | BCL10, UniProt: O95999 |
Catalog # | abx025858 |
Price | please inquire |
Order / More Info | B-Cell Lymphoma/leukemia 10 (BCL10) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950