B-Cell Lymphoma/leukemia 10 (BCL10) Antibody from ABBEXA LTD

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Antigenic SpecificityB-Cell Lymphoma/leukemia 10 (BCL10)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, IF/ICC, FCM
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThis gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
ImmunogenKLH-conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human BCL10.
Other NamesB-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, BCL10, CARD- containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CED- 3/ICH-1 prodomain homologous E10-like regulator, CIPER, CLAP, Cellular homolog of vCARMEN, Cellular-E10, Mammali, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, cCARMEN, c-E10, Mammalian CARD-containing adapter molecule E10, mE10, CARMEN, B-cell CLL/lymphoma 10, B-cell CLL/lymphoma 10, B-cell CLL/lymphoma 10 , B-cell CLL/lymphoma 10 , B-cell lymphoma/leukemia 10, B-cell lymphoma/leukemia 10, B-cell lymphoma/leukemia 10 , B-cell lymphoma/leukemia 10 , BCL10, BCL10, BCL10 , BCL10 , CARD- containing molecule enhancing NF-kappa-B, CARD- containing molecule enhancing NF-kappa-B, CARD- containing molecule enhancing NF-kappa-B , CARD- containing molecule enhancing NF-kappa-B , CARD-like apoptotic protein, CARD-like apoptotic protein, CARD-like apoptotic protein , CARD-like apoptoti
Gene, Accession #BCL10, UniProt: O95999
Catalog #abx025858
Priceplease inquire
Order / More InfoB-Cell Lymphoma/leukemia 10 (BCL10) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950

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