Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) antibody, protein, ELISA kits.
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| Antigenic Specificity | Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. The gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. |
| Immunogen | KLH-conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human DDR1. |
| Other Names | CAK, CD167, CD167 antigen-like family member A, Cell adhesion kinase, DDR, DDR1, discoidin domain receptor family, member 1, discoidin domain receptor tyrosine kinase 1, Discoidin receptor tyrosine kinase, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, HGK2, mammarian carcinoma kinase 10, Mammary carcinoma kinase 10, MCK-10, MCK10, NEP, neuroepithelial tyrosine kinase, neurotrophic tyrosine kinase, receptor, type 4, NTRK4, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, PTK3, PTK3A, PTK3A protein tyrosine kinase 3A, RTK6, TRK E, TRKE, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CD167a antigen, Epithelial discoidin domain receptor 1 precursor, Protein-tyrosine kinase RTK 6, Tyrosine- protein kinase CAK, CD167a, CAK, CAK, CAK , CAK , CD167, CD167, CD167 , CD167 , CD167 antigen-like family member A, CD167 antigen-like family member A, CD167 antigen-like family member A , CD167 antigen-like family member A , Cell adhesi |
| Gene, Accession # | NCBI: NP_001189450.1, NP_001189451.1, NP_001189452.1, NP_001945.3, NP_054699.2, NP_054700.2, UniProt: Q08345 |
| Catalog # | abx033583 |
| Price | please inquire |
| Order / More Info | Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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