Homeobox Protein NANOG (NANOG) Antibody from ABBEXA LTD

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Antigenic SpecificityHomeobox Protein NANOG (NANOG)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size80 µl, 400 µl,
Concentration1 mg/ml
ApplicationsELISA, WB, IHC, IF/ICC, FCM
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DescriptionNANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.
ImmunogenKLH-conjugated synthetic peptide between 15-49 amino acids from the N-terminal region of human NANOG.
Other NamesHomeobox protein NANOG, NANOG, Homeobox transcription factor Nanog, hNanog, ECAT4, ENK, ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Nanog homeobox, 2410002E02Rik, ENK, ecat4, early embryo specific expression NK family, HGNC:20857, homeobox transcription factor Nanog-delta 48, Homeobox protein NANOG, Homeobox protein NANOG, Homeobox protein NANOG , Homeobox protein NANOG , NANOG, NANOG, NANOG , NANOG , Homeobox transcription factor Nanog, Homeobox transcription factor Nanog, Homeobox transcription factor Nanog , Homeobox transcription factor Nanog , hNanog, hNanog, hNanog , hNanog , ECAT4, ECAT4, ECAT4 , ECAT4 , ENK, ENK, ENK , ENK , ES cell-associated protein 4, ES cell-associated protein 4, ES cell-associated protein 4 , ES cell-associated protein 4 , Early embryo specific expression NK-type homeobox protein, Early embryo specific expression NK-type homeobox protein, Early embryo specific expression NK-type homeobox protein , Early
Gene, Accession #Gene ID: 79923, UniProt: Q9H9S0
Catalog #abx028376
Priceplease inquire
Order / More InfoHomeobox Protein NANOG (NANOG) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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