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Antigenic Specificity | Homeobox Protein NANOG (NANOG) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | 1 mg/ml |
Applications | ELISA, WB, IHC, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation. |
Immunogen | KLH-conjugated synthetic peptide between 15-49 amino acids from the N-terminal region of human NANOG. |
Other Names | Homeobox protein NANOG, NANOG, Homeobox transcription factor Nanog, hNanog, ECAT4, ENK, ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Nanog homeobox, 2410002E02Rik, ENK, ecat4, early embryo specific expression NK family, HGNC:20857, homeobox transcription factor Nanog-delta 48, Homeobox protein NANOG, Homeobox protein NANOG, Homeobox protein NANOG , Homeobox protein NANOG , NANOG, NANOG, NANOG , NANOG , Homeobox transcription factor Nanog, Homeobox transcription factor Nanog, Homeobox transcription factor Nanog , Homeobox transcription factor Nanog , hNanog, hNanog, hNanog , hNanog , ECAT4, ECAT4, ECAT4 , ECAT4 , ENK, ENK, ENK , ENK , ES cell-associated protein 4, ES cell-associated protein 4, ES cell-associated protein 4 , ES cell-associated protein 4 , Early embryo specific expression NK-type homeobox protein, Early embryo specific expression NK-type homeobox protein, Early embryo specific expression NK-type homeobox protein , Early |
Gene, Accession # | Gene ID: 79923, UniProt: Q9H9S0 |
Catalog # | abx028376 |
Price | please inquire |
Order / More Info | Homeobox Protein NANOG (NANOG) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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