JNK1 (pT183/Y185) Antibody from ABBEXA LTD
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|---|---|
| Antigenic Specificity | JNK1 (pT183/Y185) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T183/Y185 of human JNK1. |
| Other Names | JNK1, PRKM8, SAPK1, SAPK1C, Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, JNK-46, Stress-activated protein kinase 1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, MAPK8, JNK, JNK1A2, JNK21B1/2, JNK1, JNK1, JNK1 , JNK1 , PRKM8, PRKM8, PRKM8 , PRKM8 , SAPK1, SAPK1, SAPK1 , SAPK1 , SAPK1C, SAPK1C, SAPK1C , SAPK1C , Mitogen-activated protein kinase 8, Mitogen-activated protein kinase 8, Mitogen-activated protein kinase 8 , Mitogen-activated protein kinase 8 , MAP kinase 8, MAP kinase 8, MAP kinase 8 , MAP kinase 8 , MAPK 8, MAPK 8, MAPK 8 , MAPK 8 , JNK-46, JNK-46, JNK-46 , JNK-46 , Stress-activated protein kinase 1c, Stress-activated protein kinase 1c, Stress-activated protein kinase 1c , Stress-activated protein kinase 1c , Stress-activated protein kinase JNK1, Stress-activated protein kinase JNK1, Stress-activated protein kinase JNK1 , Stress-activated protein kinase JNK1 , c-Jun N-terminal kinase 1, c-Jun N-terminal kinase 1, c-Jun N-terminal |
| Gene, Accession # | UniProt: P45983 |
| Catalog # | abx032107 |
| Price | please inquire |
| Order / More Info | JNK1 (pT183/Y185) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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