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Antigenic Specificity | Polypyrimidine Tract-Binding Protein 1 (PTBP1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PTBP1 antibody is a Rabbit polyclonal antibody against PTBP1. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been describ. |
Immunogen | Recombinant protein of human PTBP1. |
Other Names | HNRNPI, HNRPI, PTB, PTB-T, PTB2, PTB3, PTB4, pPTB, Heterogeneous Nuclear Ribonucleoprotein I, 57 kDa RNA-binding protein PPTB-1, Polypyrimidine tract-binding protein 1, hnRNP I, PTBP1, PTB-1, HNRNP-I, polypyrimidine tract binding protein 1, RNA binding protein, heterogeneous nuclear ribonucleoprotein polypeptide I, polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I), HNRNPI, HNRNPI, HNRNPI , HNRNPI , HNRPI, HNRPI, HNRPI , HNRPI , PTB, PTB, PTB , PTB , PTB-T, PTB-T, PTB-T , PTB-T , PTB2, PTB2, PTB2 , PTB2 , PTB3, PTB3, PTB3 , PTB3 , PTB4, PTB4, PTB4 , PTB4 , pPTB, pPTB, pPTB , pPTB , Heterogeneous Nuclear Ribonucleoprotein I, Heterogeneous Nuclear Ribonucleoprotein I, Heterogeneous Nuclear Ribonucleoprotein I , Heterogeneous Nuclear Ribonucleoprotein I , 57 kDa RNA-binding protein PPTB-1, 57 kDa RNA-binding protein PPTB-1, 57 kDa RNA-binding protein PPTB-1 , 57 kDa RNA-binding protein PPTB-1 , Polypyrimidine tract-binding protein 1, Polypyrimidine |
Gene, Accession # | PTBP1, Gene ID: 5725, UniProt: P26599 |
Catalog # | abx001513 |
Price | please inquire |
Order / More Info | Polypyrimidine Tract-Binding Protein 1 (PTBP1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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