Bim BH3 Domain Antibody from ABBEXA LTD

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Antigenic SpecificityBim BH3 Domain
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionBim belongs to the BCL-2 protein family. BCL-2 family members form hetero or homodimers and act as anti or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bim contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X (L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection.
ImmunogenKLH-conjugated synthetic peptide between 130-165 amino acids from human Bim BH3 Domain.
Other NamesBCL2L11, BIM, Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, BCL2L11, BCL2L11 , BCL2L11 , BCL2L11, BIM, BIM , BIM , BIM, Bcl-2-like protein 11, Bcl-2-like protein 11 , Bcl-2-like protein 11 , Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, Bcl2-interacting mediator of cell death , Bcl2-interacting mediator of cell death , Bcl2-interacting mediator of cell death
Gene, Accession #NCBI: NP_001191035.1, NP_001191036.1, NP_001191037.1, NP_001191038.1, NP_001191039.1, NP_001191040.1, NP_001191041.1, NP_001191042.1, NP_006529.1, NP_619527.1, NP_619528.1, NP_619529.1, NP_619530.1, NP_619531.1, NP_61953, UniProt: O43521
Catalog #abx027202
Priceplease inquire
Order / More InfoBim BH3 Domain Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950

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