Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) Antibody from ABBEXA LTD
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| Antigenic Specificity | Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, WB, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) antibody is a Rabbit polyclonal antibody for the detection of ABCA4. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. |
| Immunogen | ABCA4 |
| Other Names | ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1, ABC10, ABC10, ABC10 , ABC10 , ABCR, ABCR, ABCR , ABCR , ARMD2, ARMD2, ARMD2 , ARMD2 , CORD3, CORD3, CORD3 , CORD3 , FFM, FFM, FFM , FFM , RMP, RMP, RMP , RMP , RP19, RP19, RP19 , RP19 , STGD, STGD, STGD , STGD , STGD1, STGD1, STGD1 , STGD1 |
| Gene, Accession # | ABCA4, Gene ID: 24, UniProt: P78363 |
| Catalog # | abx147862 |
| Price | please inquire |
| Order / More Info | Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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