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Antigenic Specificity | Matrix Metalloproteinase 2 (MMP2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Matrix Metalloproteinase 2 (MMP2) antibody is a Rabbit polyclonal antibody for the detection of MMP2. This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
Other Names | MMP2, Matrix Metalloproteinase 2, CLG4, CLG4A, MMP-II, MONA, TBE-1, PEX, Gelatinase A, 72kDa Gelatinase, 72kDa Type IV Collagenase, MMP2, MMP2, MMP2 , MMP2 , Matrix Metalloproteinase 2, Matrix Metalloproteinase 2, Matrix Metalloproteinase 2 , Matrix Metalloproteinase 2 , CLG4, CLG4, CLG4 , CLG4 , CLG4A, CLG4A, CLG4A , CLG4A , MMP-II, MMP-II, MMP-II , MMP-II , MONA, MONA, MONA , MONA , TBE-1, TBE-1, TBE-1 , TBE-1 , PEX, PEX, PEX , PEX , Gelatinase A, Gelatinase A, Gelatinase A , Gelatinase A , 72kDa Gelatinase, 72kDa Gelatinase, 72kDa Gelatinase , 72kDa Gelatinase , 72kDa Type IV Collagenase, 72kDa Type IV Collagenase, 72kDa Type IV Collagenase , 72kDa Type IV Collagenase |
Gene, Accession # | MMP2, Gene ID: 4313, UniProt: P08253 |
Catalog # | abx011170 |
Price | please inquire |
Order / More Info | Matrix Metalloproteinase 2 (MMP2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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