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Antigenic Specificity | RNA Polymerase I Subunit A (POLR1A) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity). |
Immunogen | KLH-conjugated synthetic peptide between 1437-1465 amino acids from the C-terminal region of human POLR1A. |
Other Names | POLR1A, DNA-directed RNA polymerase I subunit RPA1, A190, DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I subunit A, RNA polymerase I 194 kDa subunit, POLR1A, POLR1A, POLR1A , POLR1A , DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA1 , DNA-directed RNA polymerase I subunit RPA1 , A190, A190, A190 , A190 , DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I largest subunit , DNA-directed RNA polymerase I largest subunit , DNA-directed RNA polymerase I subunit A, DNA-directed RNA polymerase I subunit A, DNA-directed RNA polymerase I subunit A , DNA-directed RNA polymerase I subunit A , RNA polymerase I 194 kDa subunit, RNA polymerase I 194 kDa subunit, RNA polymerase I 194 kDa subunit , RNA polymerase I 194 kDa subunit |
Gene, Accession # | POLR1A, UniProt: O95602 |
Catalog # | abx030684 |
Price | please inquire |
Order / More Info | RNA Polymerase I Subunit A (POLR1A) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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