RNA Polymerase I Subunit A (POLR1A) Antibody from ABBEXA LTD

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Antigenic SpecificityRNA Polymerase I Subunit A (POLR1A)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).
ImmunogenKLH-conjugated synthetic peptide between 1437-1465 amino acids from the C-terminal region of human POLR1A.
Other NamesPOLR1A, DNA-directed RNA polymerase I subunit RPA1, A190, DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I subunit A, RNA polymerase I 194 kDa subunit, POLR1A, POLR1A, POLR1A , POLR1A , DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA1 , DNA-directed RNA polymerase I subunit RPA1 , A190, A190, A190 , A190 , DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I largest subunit , DNA-directed RNA polymerase I largest subunit , DNA-directed RNA polymerase I subunit A, DNA-directed RNA polymerase I subunit A, DNA-directed RNA polymerase I subunit A , DNA-directed RNA polymerase I subunit A , RNA polymerase I 194 kDa subunit, RNA polymerase I 194 kDa subunit, RNA polymerase I 194 kDa subunit , RNA polymerase I 194 kDa subunit
Gene, Accession #POLR1A, UniProt: O95602
Catalog #abx030684
Priceplease inquire
Order / More InfoRNA Polymerase I Subunit A (POLR1A) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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