Edit |   |
---|---|
Antigenic Specificity | Cystatin-B (CSTB) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). |
Immunogen | KLH-conjugated synthetic peptide between 10-39 amino acids from the Central region of human CSTB. |
Other Names | CPI-B, CST6, CSTB, cystatin B (stefin B), Cystatin-B, CYTB, EPM1, Liver thiol proteinase inhibitor, PME, stefin B, Stefin-B, STFB, Liver thiol proteinase inhibitor Stefin-B, ULD, EPM1A, CPI-B, CPI-B, CPI-B , CPI-B , CST6, CST6, CST6 , CST6 , CSTB, CSTB, CSTB , CSTB , cystatin B (stefin B), cystatin B (stefin B), cystatin B (stefin B) , cystatin B (stefin B) , Cystatin-B, Cystatin-B, Cystatin-B , Cystatin-B , CYTB, CYTB, CYTB , CYTB , EPM1, EPM1, EPM1 , EPM1 , Liver thiol proteinase inhibitor, Liver thiol proteinase inhibitor, Liver thiol proteinase inhibitor , Liver thiol proteinase inhibitor , PME, PME, PME , PME , stefin B, stefin B, stefin B , stefin B , Stefin-B, Stefin-B, Stefin-B , Stefin-B , STFB, STFB, STFB , STFB , Liver thiol proteinase inhibitor Stefin-B, Liver thiol proteinase inhibitor Stefin-B, Liver thiol proteinase inhibitor Stefin-B , Liver thiol proteinase inhibitor Stefin-B , ULD, ULD, ULD , ULD , EPM1A, EPM1A, EPM1A , EPM1A |
Gene, Accession # | UniProt: P04080 |
Catalog # | abx027992 |
Price | please inquire |
Order / More Info | Cystatin-B (CSTB) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950