5-Hydroxytryptamine Receptor 2C (HTR2C) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-5-Hydroxytryptamine Receptor 2C (HTR2C) antibody, protein, ELISA kits.
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| Antigenic Specificity | 5-Hydroxytryptamine Receptor 2C (HTR2C) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. |
| Immunogen | KLH-conjugated synthetic peptide between 253-282 amino acids from the Central region of human HTR2C. |
| Other Names | 5-hydroxytryptamine 2C receptor, 5H2C, 5HT-1C, 5HT1C, 5HT2C, HTR1C, HTR2C, Serotonin receptor, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 1C, Serotonin receptor 2C, htr2c-, 5-hydroxytryptamine 2C receptor, 5-hydroxytryptamine 2C receptor, 5-hydroxytryptamine 2C receptor , 5-hydroxytryptamine 2C receptor , 5H2C, 5H2C, 5H2C , 5H2C , 5HT-1C, 5HT-1C, 5HT-1C , 5HT-1C , 5HT1C, 5HT1C, 5HT1C , 5HT1C , 5HT2C, 5HT2C, 5HT2C , 5HT2C , HTR1C, HTR1C, HTR1C , HTR1C , HTR2C, HTR2C, HTR2C , HTR2C , Serotonin receptor, Serotonin receptor, Serotonin receptor , Serotonin receptor , 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 2C , 5-hydroxytryptamine receptor 2C , 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 1C , 5-hydroxytryptamine receptor 1C , Serotonin receptor 2C, Serotonin receptor 2C, Serotonin receptor 2C , Serotonin receptor 2C , htr2c-, htr2c-, htr2c- , htr2c- |
| Gene, Accession # | HTR2C, UniProt: P28335 |
| Catalog # | abx027675 |
| Price | please inquire |
| Order / More Info | 5-Hydroxytryptamine Receptor 2C (HTR2C) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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