Edit |   |
---|---|
Antigenic Specificity | Nuclease-Sensitive Element-Binding Protein 1 (YBX1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. |
Immunogen | KLH-conjugated synthetic peptide between 149-178 amino acids from the Central region of human YBX1. |
Other Names | YBX1, NSEP1, YB1, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Y-box transcription factor, Y-box-binding protein 1, BP-8, CSDB, DBPB, YB-1, CSDA2, NSEP-1, MDR-NF1, YBX1, YBX1, YBX1 , YBX1 , NSEP1, NSEP1, NSEP1 , NSEP1 , YB1, YB1, YB1 , YB1 , Nuclease-sensitive element-binding protein 1, Nuclease-sensitive element-binding protein 1, Nuclease-sensitive element-binding protein 1 , Nuclease-sensitive element-binding protein 1 , CCAAT-binding transcription factor I subunit A, CCAAT-binding transcription factor I subunit A, CCAAT-binding transcription factor I subunit A , CCAAT-binding transcription factor I subunit A , DNA-binding protein B, DNA-binding protein B, DNA-binding protein B , DNA-binding protein B , Enhancer factor I subunit A, Enhancer factor I subunit A, Enhancer factor I subunit A , Enhancer factor I subunit A , Y-box transcription factor, Y-box transcription factor, Y |
Gene, Accession # | NCBI: NP_004550.2, UniProt: P67809 |
Catalog # | abx031312 |
Price | please inquire |
Order / More Info | Nuclease-Sensitive Element-Binding Protein 1 (YBX1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950