GTPase HRas (HRAS) Antibody from ABBEXA LTD
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| Antigenic Specificity | GTPase HRas (HRAS) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. These proteins function in signal transduction pathways. They can bind GTP and GDP, and they have intrinsic GTPase activity. HRAS undergoes a continuous cycle of de and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in the HRAS gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. |
| Immunogen | KLH-conjugated synthetic peptide between 104-128 amino acids from the Central region of human HRAS. |
| Other Names | HRAS, HRas Proto-Oncogene, GTPase, HRAS1, V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog, Harvey Rat Sarcoma Viral Oncogene Homolog, Transforming Protein P21, GTPase HRas, P21ras, Ras Family Small GTP Binding Protein H-Ras, Harvey Rat Sarcoma Viral Oncoprotein, Transformation Gene: Oncogene HAMSV, GTP- And GDP-Binding Peptide B, Ha-Ras1 Proto-Oncoprotein, C-Has/Bas P21 Protein, P19 H-RasIDX Protein, EC 3.6.5.2, C-BAS/HAS, C-HA-RAS1, H-RASIDX, C-H-RAS, H-Ras-1, C-H-Ras, Ha-Ras, HAMSV, RASH1, CTLO, HRAS, HRAS, HRAS , HRAS , HRas Proto-Oncogene, GTPase, HRas Proto-Oncogene, GTPase, HRas Proto-Oncogene, GTPase , HRas Proto-Oncogene, GTPase , HRAS1, HRAS1, HRAS1 , HRAS1 , V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog, V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog, V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog , V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog , Harvey Rat Sarcoma Viral Oncogene Homolog, Harvey Rat Sarcoma Viral Oncogene Homolog, Harvey Rat Sarcoma |
| Gene, Accession # | HRAS, Gene ID: 3265, NCBI: NP_001123914.1, NP_005334.1, NP_789765.1, UniProt: P01112 |
| Catalog # | abx033667 |
| Price | please inquire |
| Order / More Info | GTPase HRas (HRAS) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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