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Antigenic Specificity | B-Cell Lymphoma/leukemia 10 (BCL10) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µl, |
Concentration | 1 mg/ml |
Applications | ELISA, WB, IHC, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN.Entrez Protein NP_003912.It is a protein containing a caspase recruitment domain (CARD).It plays an important role in apoptosis and activating NF-kappaB.The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling.Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma.MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. |
Immunogen | Purified recombinant fragment of human BCL-10 expressed in E. coli. |
Other Names | B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, BCL10, CARD- containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CED- 3/ICH-1 prodomain homologous E10-like regulator, CIPER, CLAP, Cellular homolog of vCARMEN, Cellular-E10, Mammali, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, cCARMEN, c-E10, Mammalian CARD-containing adapter molecule E10, mE10, CARMEN, B-cell CLL/lymphoma 10, B-cell CLL/lymphoma 10, B-cell CLL/lymphoma 10 , B-cell CLL/lymphoma 10 , B-cell lymphoma/leukemia 10, B-cell lymphoma/leukemia 10, B-cell lymphoma/leukemia 10 , B-cell lymphoma/leukemia 10 , BCL10, BCL10, BCL10 , BCL10 , CARD- containing molecule enhancing NF-kappa-B, CARD- containing molecule enhancing NF-kappa-B, CARD- containing molecule enhancing NF-kappa-B , CARD- containing molecule enhancing NF-kappa-B , CARD-like apoptotic protein, CARD-like apoptotic protein, CARD-like apoptotic protein , CARD-like apoptoti |
Gene, Accession # | Gene ID: 8915 |
Catalog # | abx015774 |
Price | please inquire |
Order / More Info | B-Cell Lymphoma/leukemia 10 (BCL10) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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