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Antigenic Specificity | Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. The second proline-rich region may interact with actin targeting the kinase to a specific location in the cell. ERK5 is autophosphorylated on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent. |
Immunogen | KLH-conjugated synthetic peptide between 776-805 amino acids from the C-terminal region of human MAPK7. |
Other Names | Big MAP kinase 1, BMK 1, BMK 1 kinase, BMK-1, BMK1, BMK1 Kinase, ERK 4, ERK 5, ERK-5, ERK4, ERK5, Extracellular Signal Regulated Kinase 5, Extracellular signal-regulated kinase 5, MAP kinase 7, MAPK 7, MAPK7, Mitogen Activated Protein Kinase 7, Mitogen-activated protein kinase 7, OTTHUMP00000065906, OTTHUMP00000065907, PRKM 7, PRKM7, PROTEIN KINASE, MITOGEN-ACTIVATED, Big MAP kinase 1, Big MAP kinase 1, Big MAP kinase 1 , Big MAP kinase 1 , BMK 1, BMK 1, BMK 1 , BMK 1 , BMK 1 kinase, BMK 1 kinase, BMK 1 kinase , BMK 1 kinase , BMK-1, BMK-1, BMK-1 , BMK-1 , BMK1, BMK1, BMK1 , BMK1 , BMK1 Kinase, BMK1 Kinase, BMK1 Kinase , BMK1 Kinase , ERK 4, ERK 4, ERK 4 , ERK 4 , ERK 5, ERK 5, ERK 5 , ERK 5 , ERK-5, ERK-5, ERK-5 , ERK-5 , ERK4, ERK4, ERK4 , ERK4 , ERK5, ERK5, ERK5 , ERK5 , Extracellular Signal Regulated Kinase 5, Extracellular Signal Regulated Kinase 5, Extracellular Signal Regulated Kinase 5 , Extracellular Signal Regulated Kinase 5 , Extracellular signal-regulated kinase |
Gene, Accession # | UniProt: Q13164 |
Catalog # | abx033440 |
Price | please inquire |
Order / More Info | Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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