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Antigenic Specificity | Bone Morphogenetic Protein Receptor 1A (BMPR1A) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPRIA binds BMP4 with high-affinity in solution and is a potent BMP-4 antagonist in vitro. In adult tissues, BMPRIA is widely expressed, with the highest expression levels detected in skeletal muscle. BMPRIA is also widely expressed during embryogenesis. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BMPR1A. |
Other Names | ALK3, SKR5, CD292, ACVRLK3, 10q23del, BMPR1A, Bone morphogenetic protein receptor type-1A, Activin receptor-like kinase 3, Serine/threonine-protein kinase receptor R5, bone morphogenetic protein receptor, type IA, HGNC:1076, activin A receptor, type II-like kinase 3, BMP type-1A receptor, BMPR-1A, ALK-3, ALK3, ALK3, ALK3 , ALK3 , SKR5, SKR5, SKR5 , SKR5 , CD292, CD292, CD292 , CD292 , ACVRLK3, ACVRLK3, ACVRLK3 , ACVRLK3 , 10q23del, 10q23del, 10q23del , 10q23del , BMPR1A, BMPR1A, BMPR1A , BMPR1A , Bone morphogenetic protein receptor type-1A, Bone morphogenetic protein receptor type-1A, Bone morphogenetic protein receptor type-1A , Bone morphogenetic protein receptor type-1A , Activin receptor-like kinase 3, Activin receptor-like kinase 3, Activin receptor-like kinase 3 , Activin receptor-like kinase 3 , Serine/threonine-protein kinase receptor R5, Serine/threonine-protein kinase receptor R5, Serine/threonine-protein kinase receptor R5 , Serine/threonine-protein kinase receptor |
Gene, Accession # | UniProt: P36894 |
Catalog # | abx031356 |
Price | please inquire |
Order / More Info | Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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