LIMK1 (pT508) Antibody from ABBEXA LTD
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| Antigenic Specificity | LIMK1 (pT508) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µl, 100 µl, 200 µl, |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LIMK1 (pT508) antibody is a Rabbit polyclonal antibody against LIMK1 (pT508). There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T508 of human LIMK1. |
| Other Names | kinase LIMK1, KIZ-1, LIM domain kinase 1, LIMK, LIMK-1, LIMK1, kinase LIMK1, kinase LIMK1, kinase LIMK1 , kinase LIMK1 , KIZ-1, KIZ-1, KIZ-1 , KIZ-1 , LIM domain kinase 1, LIM domain kinase 1, LIM domain kinase 1 , LIM domain kinase 1 , LIMK, LIMK, LIMK , LIMK , LIMK-1, LIMK-1, LIMK-1 , LIMK-1 , LIMK1, LIMK1, LIMK1 , LIMK1 |
| Gene, Accession # | LIMK1, Gene ID: 3984, UniProt: P53667 |
| Catalog # | abx000434 |
| Price | please inquire |
| Order / More Info | LIMK1 (pT508) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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