26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody from ABBEXA LTD
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| Antigenic Specificity | 26S Proteasome Regulatory Subunit 6A (PSMC3) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, monkey, rat |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 100 µl, |
| Concentration | 1 mg/ml |
| Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | 26S Proteasome Regulatory Subunit 6A (PSMC3) antibody is a Mouse monoclonal against 26S Proteasome Regulatory Subunit 6A (PSMC3). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. |
| Immunogen | Purified recombinant fragment of human PSMC3 (AA: 53-152) expressed in E. Coli. |
| Other Names | PSMC3, Proteasome 26S Subunit, ATPase 3, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3, 26S Proteasome AAA-ATPase Subunit RPT5, 26S Proteasome Regulatory Subunit 6A, Proteasome Subunit P50, Tat-Binding Protein 1, TBP1, Human Immunodeficiency Virus Tat Transactivator Binding Protein-1, 26S Protease Regulatory Subunit 6A, Testicular Secretory Protein Li 42, Proteasome 26S Subunit ATPase 3, TBP-1, PSMC3, PSMC3, PSMC3 , PSMC3 , Proteasome 26S Subunit, ATPase 3, Proteasome 26S Subunit, ATPase 3, Proteasome 26S Subunit, ATPase 3 , Proteasome 26S Subunit, ATPase 3 , Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 , Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 , 26S Proteasome AAA-ATPase Subunit RPT5, 26S Proteasome AAA-ATPase Subunit RPT5, 26S Proteasome AAA-ATPase Subunit RPT5 , 26S Proteasome AAA-ATPase Subunit RPT5 , 26S Proteasome Regulatory Subunit |
| Gene, Accession # | PSMC3, Gene ID: 5702, NCBI: NM_002804, UniProt: P17980 |
| Catalog # | abx224302 |
| Price | please inquire |
| Order / More Info | 26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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