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Antigenic Specificity | Angiopoietin-1 Receptor / TIE2 (TEK) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The TIE2 receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TIE2 is closely related to the TIE receptor tyrosine kinase. |
Immunogen | KLH-conjugated synthetic peptide between 758-789 amino acids from the C-terminal region of human TEK (TIE2). |
Other Names | Angiopoietin-1 receptor, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, hTIE2, p140 TEK, TEK, TIE2, Tyrosine-protein, CD202B, TIE-2, VMCM, VMCM1, Endothelial tyrosine kinase, Tyrosine kinase with Ig and EGF homology domains-2, p140 TEK, ANG-R-Tie2, Angiopoietin Receptor Tie2, TEK Tyrosine Kinase, Endothelial, Tyrosine Kinase, Endothelial, CD202-B, Angiopoietin-1 receptor, Angiopoietin-1 receptor, Angiopoietin-1 receptor , Angiopoietin-1 receptor , Tunica interna endothelial cell kinase, Tunica interna endothelial cell kinase, Tunica interna endothelial cell kinase , Tunica interna endothelial cell kinase , Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TEK , Tyrosine-protein kinase receptor TEK , Tyrosine-protein kinase receptor TIE-2, Tyrosine-protein kinase receptor TIE-2, Tyrosine-protein kinase receptor TIE-2 , Tyrosine-protein kinase receptor TIE |
Gene, Accession # | NCBI: NP_000450.2, UniProt: Q02763 |
Catalog # | abx033613 |
Price | please inquire |
Order / More Info | Angiopoietin-1 Receptor / TIE2 (TEK) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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