Optineurin (OPTN) Antibody from ABBEXA LTD
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| Antigenic Specificity | Optineurin (OPTN) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | OPTN antibody is a Rabbit polyclonal antibody against OPTN. This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. |
| Immunogen | Recombinant protein of human OPTN. |
| Other Names | NRP, FIP2, HIP7, HYPL, ALS12, GLC1E, TFIIIA-INTP, OPTN, Optineurin, E3-14.7K-interacting protein, FIP-2, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, Optic neuropathy-inducing protein, Transcription factor IIIA-interacting protein, NRP, NRP, NRP , NRP , FIP2, FIP2, FIP2 , FIP2 , HIP7, HIP7, HIP7 , HIP7 , HYPL, HYPL, HYPL , HYPL , ALS12, ALS12, ALS12 , ALS12 , GLC1E, GLC1E, GLC1E , GLC1E , TFIIIA-INTP, TFIIIA-INTP, TFIIIA-INTP , TFIIIA-INTP , OPTN, OPTN, OPTN , OPTN , Optineurin, Optineurin, Optineurin , Optineurin , E3-14.7K-interacting protein, E3-14.7K-interacting protein, E3-14.7K-interacting protein , E3-14.7K-interacting protein , FIP-2, FIP-2, FIP-2 , FIP-2 , Huntingtin yeast partner L, Huntingtin yeast partner L, Huntingtin yeast partner L , Huntingtin yeast partner L , Huntingtin-interacting protein 7, Huntingtin-interacting protein 7, Huntingtin-interacting protein 7 , Huntingtin-interacting |
| Gene, Accession # | OPTN, Gene ID: 10133, UniProt: Q96CV9 |
| Catalog # | abx001525 |
| Price | please inquire |
| Order / More Info | Optineurin (OPTN) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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