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Antigenic Specificity | Ubiquitin-Activating Enzyme 7 (UBA7) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The modification of proteins with ubiquitin is an important cellular mechanism for targeting.Tissue specificity: Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RAR alpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. |
Immunogen | Purified recombinant fragment of human UBE1L expressed in E. Coli. |
Other Names | D8, MGC12713, UBA1, ubiquitin-activating enzyme E1 homolog B, UBA1B, UBA7, ubiquitin-activating enzyme E1, UBE1L, UBE2, Ubiquitin-activating enzyme 7, Ubiquitin-activating enzyme E1 homolog, ubiquitin-activating enzyme E1-like, ubiquitin-activating enzyme E1-related protein, ubiquitin-activating enzyme-2, ubiquitin-like modifier activating enzyme 7, Ubiquitin-like modifier-activating enzyme 7, D8, D8, D8 , D8 , MGC12713, MGC12713, MGC12713 , MGC12713 , UBA1, UBA1, UBA1 , UBA1 , ubiquitin-activating enzyme E1 homolog B, ubiquitin-activating enzyme E1 homolog B, ubiquitin-activating enzyme E1 homolog B , ubiquitin-activating enzyme E1 homolog B , UBA1B, UBA1B, UBA1B , UBA1B , UBA7, UBA7, UBA7 , UBA7 , ubiquitin-activating enzyme E1, ubiquitin-activating enzyme E1, ubiquitin-activating enzyme E1 , ubiquitin-activating enzyme E1 , UBE1L, UBE1L, UBE1L , UBE1L , UBE2, UBE2, UBE2 , UBE2 , Ubiquitin-activating enzyme 7, Ubiquitin-activating enzyme 7, Ubiquitin-activating enzyme 7 , U |
Gene, Accession # | UBA7, Gene ID: 7318, UniProt: P41226 |
Catalog # | abx011667 |
Price | please inquire |
Order / More Info | Ubiquitin-Activating Enzyme 7 (UBA7) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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