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Antigenic Specificity | Cyclin-Dependent Kinase 14 (Cdk14) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity). |
Immunogen | KLH-conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14. |
Other Names | Cdk14, Kiaa0834, Pftk1, Cyclin-dependent kinase 14, Cell division protein kinase 14, Serine/threonine-protein kinase PFTAIRE-1, Cdk14, Cdk14, Cdk14 , Cdk14 , Kiaa0834, Kiaa0834, Kiaa0834 , Kiaa0834 , Pftk1, Pftk1, Pftk1 , Pftk1 , Cyclin-dependent kinase 14, Cyclin-dependent kinase 14, Cyclin-dependent kinase 14 , Cyclin-dependent kinase 14 , Cell division protein kinase 14, Cell division protein kinase 14, Cell division protein kinase 14 , Cell division protein kinase 14 , Serine/threonine-protein kinase PFTAIRE-1, Serine/threonine-protein kinase PFTAIRE-1, Serine/threonine-protein kinase PFTAIRE-1 , Serine/threonine-protein kinase PFTAIRE-1 |
Gene, Accession # | UniProt: O35495 |
Catalog # | abx031006 |
Price | please inquire |
Order / More Info | Cyclin-Dependent Kinase 14 (Cdk14) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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