KSHV ORF45 Antibody from ABBEXA LTD

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Antigenic SpecificityKSHV ORF45
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionKaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma- (2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease.The genome of KSHV is 165-170 kb and contains at least 88 open reading frames.ORF45 protein encoded by an immediate-early gene in the KSHV genome is characterized as a phosphorylated protein, and it is localized in the cytoplasm of infected cells.Studies have shown that ORF45 Protein interacted with cellular IRF-7 and blocked virus-mediated phosphorylation and nuclear translocation of IRF-7.In consequence, ORF45 efficiently inhibited virus-induced production of type I IFN.Zhu et al (2003) reported that the ORF45 Protein was associated with purified virions.
ImmunogenPurified recombinant fragment of KSHV ORF45 expressed in E. coli.
Other NamesORF45, ORF45, ORF45 , ORF45 , ORF45
Gene, Accession #Gene ID: 4961474
Catalog #abx016034
Priceplease inquire
Order / More InfoKSHV ORF45 Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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