Immunoglobulin Heavy Constant Delta (IGHD) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Immunoglobulin Heavy Constant Delta (IGHD) antibody, protein, ELISA kits.
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| Antigenic Specificity | Immunoglobulin Heavy Constant Delta (IGHD) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. This antibody is supplied as crude ascites. |
| Immunogen | KLH-conjugated synthetic peptide between 37-64 amino acids from the N-terminal region of human IGHD. |
| Other Names | Ig delta chain C region, IGHD, Ig delta chain C region, Ig delta chain C region, Ig delta chain C region , Ig delta chain C region , IGHD, IGHD, IGHD , IGHD |
| Gene, Accession # | UniProt: P01880 |
| Catalog # | abx025506 |
| Price | please inquire |
| Order / More Info | Immunoglobulin Heavy Constant Delta (IGHD) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950
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