Mouse Lyn Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Mouse Lyn antibody, protein, ELISA kits.
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| Antigenic Specificity | Mouse Lyn |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Lyn acts as a positive regulator of cell movement while negatively regulating adhesion to stromal cells by inhibiting the ICAM-1-binding activity of beta-2 integrins. Acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. Involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. Induces SAPK by a MKK7-and MEKK1-dependent mechanism. The LYN > MEKK1 > MKK7 > SAPK pathway is functional in the induction of apoptosis by genotoxic agents (By similarity). Down regulates expression of stem cell growth factor receptor (KIT). Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Lyn. |
| Other Names | Lyn, Tyrosine-protein kinase Lyn, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, p53Lyn, p56Lyn, Lyn, Lyn , Lyn , Lyn, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase Lyn , Tyrosine-protein kinase Lyn , Tyrosine-protein kinase Lyn, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog , V-yes-1 Yamaguchi sarcoma viral related oncogene homolog , V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, p53Lyn, p53Lyn , p53Lyn , p53Lyn, p56Lyn, p56Lyn , p56Lyn , p56Lyn |
| Gene, Accession # | UniProt: P25911 |
| Catalog # | abx028183 |
| Price | please inquire |
| Order / More Info | Mouse Lyn Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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