Edit |   |
---|---|
Antigenic Specificity | DNA Methyltransferase 3 Like (DNMT3L) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNMT3L antibody is a Rabbit polyclonal antibody against DNMT3L. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Recombinant protein of human DNMT3L. |
Other Names | DNA (cytosine-5)-methyltransferase 3-like, DNMT3L, DNA cytosine-5)-methyltransferase 3-like, DNA (cytosine-5) methyltransferase 3-like, MGC1090, DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3-like , DNA (cytosine-5)-methyltransferase 3-like , DNMT3L, DNMT3L, DNMT3L , DNMT3L , DNA cytosine-5)-methyltransferase 3-like, DNA cytosine-5)-methyltransferase 3-like, DNA cytosine-5)-methyltransferase 3-like , DNA cytosine-5)-methyltransferase 3-like , DNA (cytosine-5) methyltransferase 3-like, DNA (cytosine-5) methyltransferase 3-like, DNA (cytosine-5) methyltransferase 3-like , DNA (cytosine-5) methyltransferase 3-like , MGC1090, MGC1090, MGC1090 , MGC1090 |
Gene, Accession # | DNMT3L, Gene ID: 29947, UniProt: Q9UJW3 |
Catalog # | abx001899 |
Price | please inquire |
Order / More Info | DNA Methyltransferase 3 Like (DNMT3L) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950