Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) Antibody from ABBEXA LTD
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| Antigenic Specificity | Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NGAL/LCN2 Antibody is a Rabbit Polyclonal antibody against NGAL. Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. |
| Immunogen | A synthetic peptide of human LCN2. |
| Other Names | LCN2, Lipocalin 2, Oncogene 24p3, Oncogene 24p6, 25 KDa Alpha-2-Microglobulin-Related Subunit Of MMP-9, Neutrophil Gelatinase-Associated Lipocalin, Siderocalin LCN2, NGAL, P25, Migration-Stimulating Factor Inhibitor, Neutrophil Gelatinase Associated Lipocalin, Lipocalin-2, 24p3, MSFI, p25, Lipocalin-2/NGAL, LCN2, LCN2, LCN2, LCN2, Lipocalin 2, Lipocalin 2, Lipocalin 2, Lipocalin 2, Oncogene 24p3, Oncogene 24p3, Oncogene 24p3, Oncogene 24p3, Oncogene 24p6, Oncogene 24p6, Oncogene 24p6, Oncogene 24p6, 25 KDa Alpha-2-Microglobulin-Related Subunit Of MMP-9, 25 KDa Alpha-2-Microglobulin-Related Subunit Of MMP-9, 25 KDa Alpha-2-Microglobulin-Related Subunit Of MMP-9, 25 KDa Alpha-2-Microglobulin-Related Subunit Of MMP-9, Neutrophil Gelatinase-Associated Lipocalin, Neutrophil Gelatinase-Associated Lipocalin, Neutrophil Gelatinase-Associated Lipocalin, Neutrophil Gelatinase-Associated Lipocalin, Siderocalin LCN2, Siderocalin LCN2, Siderocalin LCN2, Siderocalin LCN2, NGAL, NGAL, NGAL, NGAL, P25, P25, P25, P25, Migration-Stimulating Factor Inhibitor, Migration-Stimulating Factor Inhibitor, Migration-Stimulating Factor Inhibitor, Migration-Stimulating Factor Inhibitor, Neutrophil Gelatinase Associated Lipocalin, Neutrophil Gelatinase Associated Lipocalin, Neutrophil Gelatinase Associated Lipocalin, Neutrophil Gelatinase Associated Lipocalin, Lipocalin-2, Lipocalin-2, Lipocalin-2, Lipocalin-2, 24p3, 24p3, 24p3, 24p3, MSFI, MSFI, MSFI, MSFI, p25, p25, p25, p25, Lipocalin-2/NGAL, Lipocalin-2/NGAL, Lipocalin-2/NGAL, Lipocalin-2/NGAL |
| Gene, Accession # | LCN2, Gene ID: 3934, UniProt: P80188 |
| Catalog # | abx002278 |
| Price | please inquire |
| Order / More Info | Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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