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Antigenic Specificity | Caspase 10 (CASP10) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. |
Immunogen | KLH-conjugated synthetic peptide between 164-192 amino acids from the Central region of human CASP10. |
Other Names | CASP10, MCH4, Caspase 10, FLICE2, CASP 10, ICE like apoptotic protease 4, Caspase-10, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, ICE-like apoptotic protease 4, Caspase-10 subunit p23/17, Caspase-10 subunit p12, CASP-10, CASP10, CASP10, CASP10 , CASP10 , MCH4, MCH4, MCH4 , MCH4 , Caspase 10, Caspase 10, Caspase 10 , Caspase 10 , FLICE2, FLICE2, FLICE2 , FLICE2 , CASP 10, CASP 10, CASP 10 , CASP 10 , ICE like apoptotic protease 4, ICE like apoptotic protease 4, ICE like apoptotic protease 4 , ICE like apoptotic protease 4 , Caspase-10, Caspase-10, Caspase-10 , Caspase-10 , Apoptotic protease Mch-4, Apoptotic protease Mch-4, Apoptotic protease Mch-4 , Apoptotic protease Mch-4 , FAS-associated death domain protein interleukin-1B-converting enzyme 2, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FAS-associated death domain protein interleukin-1B-converting enzyme 2 , FAS-associated death domain protein |
Gene, Accession # | UniProt: Q92851 |
Catalog # | abx027314 |
Price | please inquire |
Order / More Info | Caspase 10 (CASP10) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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